Hologic Panther Fusion NATtrol

The expanding menu of Panther Fusion assays on the Panther Fusion system continues the legacy of testing precision and total lab automation that first began with the fully automated Panther system. Now, the flexibility of polymerase chain reaction (PCR) joins the power of transcription-mediated amplification (TMA) on the Panther Fusion system for multiple valuable chemistries on a single platform. These latest releases expand our diagnostic menu and consolidate testing to aid healthcare providers in diagnoses and maximize potential in the laboratory.

Leverage the benefits of the fully automated Panther Fusion system

The Panther Fusion system represents the latest innovation in Hologic diagnostic precision and automation. The Panther Fusion Respiratory assays leverage the benefits of the system as a whole, in addition to the assay-specific benefits.

Features include:

  • The combined flexibility of PCR and TMA
  • True sample-to-result automation
  • The ability to run only necessary assays and reduce expenses from unnecessary testing
  • Total nucleic acid extraction, with multiple tests from a single sample and multiplexing
  • Unit dose lyophilized reagents, which eliminate reagent waste and the need for manual reagent preparation
  • The ability to hold up to 28 cartridges, each with 12 reactions per cartridge for a total of 336 tests
  • Kits that can be reloaded as they are consumed without pausing testing

The Panther Fusion Respiratory assays

The Panther Fusion Respiratory assays for syndromic respiratory testing are the premier set of assays on the Panther Fusion system. You now can provide truly personalized patient testing with qualitative detection and differentiation of the most common respiratory viruses using a single patient sample. Each Panther Fusion Respiratory assay can be processed independently or simultaneously with other Panther Fusion and Aptima assays.

The Panther Fusion Respiratory menu leverages a legacy of expertise in respiratory viral molecular diagnostics from Hologic that began over a decade ago with the Prodesse Plus Series of respiratory assays.

Three respiratory assays comprise the IVD respiratory testing menu on the fully automated Panther Fusion system. Each is a multiplex, real-time  PCR in vitro diagnostic test. They isolate and purify nucleic acids from nasopharyngeal (NP) swab specimens obtained from patients who are symptomatic for respiratory tract infection. All 3 assays can be run from a single patient specimen loaded into the Panther Fusion system.

The Panther Fusion assays provide the flexibility to run patient-specific targets, allowing for personalized patient testing and better cost control in your lab.

  • The Panther Fusion Flu A/B/RSV assay – Qualitative detection and differentiation of influenza A virus, influenza B virus and respiratory syncytial virus
  • The Panther Fusion AdV/hMPV/RV assay – Qualitative detection and differentiation of adenovirus, human metapneumovirus and rhinovirus
  • The Panther Fusion Paraflu assay – Qualitative detection and differentiation of parainfluenza 1 virus, parainfluenza 2 virus, parainfluenza 3 virus, and parainfluenza 4 virus

Panther Fusion GBS assay

The Panther Fusion GBS assay joins the expanding molecular testing menu on the Panther Fusion system. This assay detects the gram-positive bacterium Streptococcus agalactiae (GBS) in pregnant women and so providers can prevent its transmission to their babies.4 GBS has serious long-term health consequences, including death, in newborns.

A Sensitive Assay for a Distinct Threat

This assay features world-class performance and sensitivity, answering a crucial need for GBS detection. GBS is a serious and sometimes fatal infection that is passed to infants during birth.5 GBS is a leading cause of early-onset neonatal sepsis in the United States, and it also can cause pneumonia and meningitis.5 Antibiotic prophylaxis can reduce transmission of GBS to babies when administered properly. The Panther Fusion GBS assay helps providers diagnose GBS in mothers so they can confidently determine if intrapartum prophylaxis is needed.

Intuitive Design for Real-World Need

The CDC states that accurate results are more important than rapid turnaround time for antenatal screening.5 When providers have diagnostic tools with excellent sensitivity and performance, they can deliver the highest level of care. The Panther Fusion GBS assay is a real-time PCR assay for antepartum testing with enriched vaginal and rectal swabs. It features dual-target detection of Cfb and SIP genes and 100% clinical sensitivity.4

True Flexibility and Full Automation

Run-on the Panther Fusion system, this assay offers the benefits of Panther Fusion automation, high-throughput flexibility, and ease of use, allowing for high-volume GBS testing in reference laboratories and hospitals. It may be processed, free from batching on the Panther Fusion system with other Aptima and Panther Fusion assays for women’s health, virology, respiratory, and sexually transmitted infections.

 

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