Effectiveness of hallux valgus surgery on patient quality of life: a systematic review and meta-analysis.

Background and purpose – The quality of life (QoL) of patients with hallux valgus (HV) usually improves postoperatively. Evidence regarding the effect of HV surgery on different domains of patient QoL remains inconclusive.

This systematic review and meta-analysis estimates the effect of HV surgery on patient QoL through distinguishing effects on physical domains (comprising physical function and body pain domains) using the EuroQol-5D, short form (SF) health survey-12, and SF-36 QoL scales and a visual analogue scale (VAS) score and mental and social domains using QoL scales.Patients and methods – MEDLINE, EMBASE, Cochrane Library, and Web of Science databases were systematically searched from inception to March 2019 for studies on the effect of HV surgery on patient QoL.

A standardized mean difference score was calculated for each specific QoL domain (mental, social, pain, physical, and VAS) using Cohen’s d index. The pooled effect size (ES) was estimated using a random-effects model based on the DerSimonian and Laird method.Results – From 12 published studies selected, the estimated pooled ES for QoL was 1.01 (95% confidence interval [CI] 0.52-1.51; I2 = 87%) for body pain and 0.43 (CI 0.31-0.55, I2 = 35%) for physical function. Regarding the composite mental and social domains of QoL, the pooled ES estimates were 0.24 (CI 0.00-0.47, I2 = 80%) and 0.42 (CI 0.21-0.63, I2 = 6.4%), respectively.

InVivoMAb Human AS Fc Block (Iv0017)
MBS1570042-01mg 0.1mg
EUR 295

InVivoMAb Human AS Fc Block (Iv0017)
MBS1570042-5x01mg 5x0.1mg
EUR 1045

Block 16mm For Block Heater - EACH
BLO5016 EACH
EUR 179.55

EZ Block
EZB125 125 ml
EUR 34.71

EZ Block
EZB500 500 ml
EUR 61.72

EZ Block
EZB999 1000 ml
EUR 98.99

TRU Block
MBS316734-100mg 100mg
EUR 560

TRU Block
MBS316734-5x100mg 5x100mg
EUR 2350

BLOCK ACE
MBS238969-20x4g 20x4g
EUR 585

Soft Block
24616-1 1gal
EUR 156.6
Description: 7732-18-5

Soft Block
24616-120 120ml
EUR 38.88

Soft Block
24616-500 500ml
EUR 70.2
Description: 7732-18-5

Super Block
AAA125 125 ml
EUR 19.28

Super Block
AAA500 500 ml
EUR 41.14

Super Block
AAA999 1000 ml
EUR 59.14

Peroxide Block
ACA015 15 ml
EUR 13.27

Peroxide Block
ACA125 125 ea.
EUR 20.58

Peroxide Block
ACA500 500 ml
EUR 41.14

Peroxide Block
ACA999 1000 ml
EUR 60.43

Block, PCR plate, For 1-block dry bath
BCM1412-BSWPCR1 1 pcs, 1 UNIT
EUR 435.84

Block 24x0.5ml for Flowgen Mini Block Digital - EACH
BLO2204 EACH
EUR 166.05

Block 15x1.5ml for Flowgen Mini Block Digital - EACH
BLO2206 EACH
EUR 166.05

Block 4x15ml for Flowgen Mini Block Digital - EACH
BLO2210 EACH
EUR 207.9

Block 2x50ml for Flowgen Mini Block Digital - EACH
BLO2212 EACH
EUR 207.9

Biometra TAdvanced Block Module 96 S Silver Block
AJ846-070-271 each
EUR 4512.6

Dry Block Heater 1 for a single block - EACH
BLO6014 EACH
EUR 1571.4

ELISA BSA BLOCK
MBS238280-100mL 100mL
EUR 220

ELISA BSA BLOCK
MBS238280-5x100mL 5x100mL
EUR 820

ELISA BSA BLOCK
MBS238281-500mL 500mL
EUR 415

ELISA BSA BLOCK
MBS238281-5x500mL 5x500mL
EUR 1680

ELISA BSA BLOCK
MBS238282-1L 1L
EUR 660

ELISA BSA BLOCK
MBS238282-5x1L 5x1L
EUR 2850

Block, PCR plate, for 2 or 4-block dry bath
BCM1412-BSWPCR2 1 pcs, 1 UNIT
EUR 425.48

Biometra TAdvanced Block Module 96 S Gradient Silver Block
AJ846-070-261 each
EUR 5177.5

Biotin Block Kit
B3810-002 30ml
EUR 262.8

Biotin Block Kit
B3810-005 120ml
EUR 489.6

Block Wash Buffer
I044 1000 ml
EUR 632.4
Description: Block Wash Buffer by Cygnus Technologies is available in Europe via Gentaur.

BLOCK ACE Reagent
GWB-Q00190 20 x 4g Ask for price

Heat Block Lifter
LBC20004 each
EUR 51.78

Heater block - EACH
WAT1026 EACH
EUR 1536.3

HiQTM Immuno Block
I3211-010 100ml
EUR 160.8

HiQTM Immuno Block
I3211-050 500ml
EUR 319.2

FlexCycler² block 96G
AJ844-60061-0 each Ask for price

Universal Block Buffer
TBS5013 100 ml
EUR 60

24 x 0.5mL block
CDBI-24-B each
EUR 80

15 x 1.5mL block
CDBI-24-C1 each
EUR 80

15 x 2.0mL block
CDBI-24-C2 each
EUR 80

Block, 54 x 0.5ml
H5000-05 1 PC
EUR 350.82

Block, 35 x 1.5ml
H5000-15 1 PC
EUR 350.82

Block, 35 x 2.0ml
H5000-20 1 PC
EUR 350.82

96 x 0.2mL block
PDBI-CL-96-A each
EUR 220

54 x 0.5mL block
PDBI-CL-96-B each
EUR 190

35 x 1.5mL block
PDBI-CL-96-C each
EUR 190

35 x 2.0mL block
PDBI-CL-96-D each
EUR 190

Block 40x0.2ml or PCR Strips for Flowgen Mini Block Digital - EACH
BLO2202 EACH
EUR 194.4

AgriCoat-Block | Non mammalian Protein Coat Block (5X) (100 ml)
AS18-AgriCtBlock-100 100 ml
EUR 201

Block, 24 x 12mm
H5000-12 1 PC
EUR 494.19

Block, 12 x 15ml
H5000-150 1 PC
EUR 494.19

Block, 6 x 50ml
H5000-500 1 PC
EUR 494.19

HiQ Block for IHC
B3077-010 100ml
EUR 160.8

HiQ Block for IHC
B3077-050 500ml
EUR 315.6

Purified Mouse Anti-Mouse CD16/CD32 (Mouse AS Fc Block)(2.4G2)
MBS1569797-01mg 0.1mg
EUR 340

Purified Mouse Anti-Mouse CD16/CD32 (Mouse AS Fc Block)(2.4G2)
MBS1569797-5x01mg 5x0.1mg
EUR 1235

Techne Dri Block - EACH
BLO1032 EACH
EUR 1125.9

pAd/BLOCK-iT-DEST
PVTY00782 2ug
EUR 280

96 Well Aluminum Block
81001 each
EUR 110

Block for 20 x 10mm tubes for techne dri -block heaters - EACH
Z381438-1EA EACH
EUR 221.79

WSC-2610 MyMini BLOCK
4002610 1unit
EUR 368.5
Description: Compact sized heat block incubator

ELISA BSA BLOCK Reagent
GWB-Q00212 100 ml Ask for price

ELISA BSA BLOCK Reagent
GWB-Q00213 500 ml Ask for price

ELISA BSA BLOCK Reagent
GWB-Q00214 1000 ml Ask for price

Heater block cover - EACH
WAT1022 EACH
EUR 140.4

Mini Cooling Block - EACH
VS10ICB EACH
EUR 58.05

Maxi Cooling Block - EACH
VS20ICB EACH
EUR 95.85

Neptune Block ELISA Blocking Buffer
MBS258384-100mL 100mL
EUR 160

Neptune Block ELISA Blocking Buffer
MBS258384-1L 1L
EUR 380

Neptune Block ELISA Blocking Buffer
MBS258384-500mL 500mL
EUR 260

Neptune Block ELISA Blocking Buffer
MBS258384-5x1L 5x1L
EUR 1595

Jenway Heated Cell Block
COL3006 EACH
EUR 456

Deli-Cal Block Solution
24900-250 250g
EUR 66.96
Description: 7732-18-5

Deli-Cal Block Solution
24900-500 500g
EUR 101.52
Description: 7732-18-5

Eppendorf Tube Block - EACH
BLO5022 EACH
EUR 178.2

Block/Wash 20x Concentrate
F062 50 ml
EUR 234
Description: Block/Wash 20x Concentrate by Cygnus Technologies is available in Europe via Gentaur.

Block/Wash 20x Concentrate
F062-100 100 ml
EUR 355.2
Description: Block/Wash 20x Concentrate by Cygnus Technologies is available in Europe via Gentaur.

Block/Wash 20X Concentrate
F062-1000 1000 ml
EUR 493.2
Description: Block/Wash 20X Concentrate by Cygnus Technologies is available in Europe via Gentaur.

Block-Free ELISA Reagent
M4102-250 each
EUR 542.4

Block-Free ELISA Reagent
M4102-50 each
EUR 176.4

De-Calcify Block Solution
24903-250 250g
EUR 62.64
Description: 7732-18-5

De-Calcify Block Solution
24903-500 500g
EUR 117.72
Description: 7732-18-5

OAMA04082-100MG - TRU Block
OAMA04082-100MG 0.1g
EUR 499

Paraffin Block Mailer/Holder
25340-25 1pack
EUR 71.28

Paraffin Block Mailer/Holder
25340-50 1pack
EUR 126.36

Coating Stabilizer & Block Buf
MBS318402-1L 1L
EUR 460

Coating Stabilizer & Block Buf
MBS318402-5x1L 5x1L
EUR 1945

Microscope Slide Holder Block
24764-1 1each
EUR 164.16

Cooling Block PCR WorkStation
LC4001 Ea
EUR 327.6

Microplate Thermal Block - EACH
SHA2086 EACH
EUR 1026

Techne Block Plain Thermometer
BLO2122 EACH
EUR 148.05

Heating block 96/384 Mikrotiterplates
TSB-50 each
EUR 299

block, 6 x ɸ 15mm
MICV-0615 each
EUR 80

block, 6 x ɸ 16mm
MICV-0616 each
EUR 80

AgriCoat-Block | Non mammalian Protein Coat Block (5X) (10 ml)
AS18-AgriCtBlock-10 10 ml
EUR 13

AgriCoat-Block | Non mammalian Protein Coat Block (5X) (1L ml)
AS18-AgriCtBlock-1L 1L
EUR 750

Block 54 x 0.5mL - EACH
MIX7204 EACH
EUR 508.95

Block 35 x 1.5mL - EACH
MIX7208 EACH
EUR 508.95

Block 35 x 2.0mL - EACH
MIX7210 EACH
EUR 508.95

Block, 30 x NMR tubes
BSWNMR 1 PC
EUR 294.27

Block 24 x 12mm - EACH
MIX7212 EACH
EUR 714.15

Block 12 x 15mL - EACH
MIX7214 EACH
EUR 714.15

Block 6 x 50mL - EACH
MIX7216 EACH
EUR 714.15

single 60 x 0.5mL block
AC-60-B each
EUR 2400

single 96 x 0.2mL block
AC-96-B each
EUR 2200

ENO block(AP-III-a4)
MBS130092-100mg 100mg
EUR 1065

ENO block(AP-III-a4)
MBS130092-500mg 500mg
EUR 2775

Block, 20 x HPLC/ CryoVial
BSW1232 each
EUR 149.04

Block for one Micro Plate
H5000-MP 1 PC
EUR 494.19

DUAL BLOCK, 384 WELL PCR PLATE
480133 1/pk
EUR 277.2
Description: Lab Equipment; Constant Temperature Equipment

3T3 FFPE Cell Pellet Block
AniFFPE-CP001 1 Block Ask for price
Description: Embryo

CHO FFPE Cell Pellet Block
AniFFPE-CP004 1 Block Ask for price
Description: Ovary

NSO FFPE Cell Pellet Block
AniFFPE-CP010 1 Block Ask for price
Description: Skin

H23 FFPE Cell Pellet Block
LuFFPE-CP001 1 Block Ask for price
Description: Lung

HEL FFPE Cell Pellet Block
LeFFPE-CP016 1 Block Ask for price
Description: Leukemia

PC3 FFPE Cell Pellet Block
ProFFPE-CP001 1 Block Ask for price
Description: Prostate

PA1 FFPE Cell Pellet Block
OvaFFPE-CP022 1 Block Ask for price
Description: Ovary

M14 FFPE Cell Pellet Block
MeFFPE-CP016 1 Block Ask for price
Description: Skin

C32 FFPE Cell Pellet Block
MeFFPE-CP019 1 Block Ask for price
Description: Skin

HELA FFPE Cell Pellet Block
CeFFPE-CP001 1 Block Ask for price
Description: Cervix

SIHA FFPE Cell Pellet Block
CeFFPE-CP004 1 Block Ask for price
Description: Cervix

C33A FFPE Cell Pellet Block
CeFFPE-CP010 1 Block Ask for price
Description: Cervix

HT29 FFPE Cell Pellet Block
CoFFPE-CP004 1 Block Ask for price
Description: Colon

SW48 FFPE Cell Pellet Block
CoFFPE-CP025 1 Block Ask for price
Description: Colon

MCF7 FFPE Cell Pellet Block
BreFFPE-CP013 1 Block Ask for price
Description: Breast

T47D FFPE Cell Pellet Block
BreFFPE-CP019 1 Block Ask for price
Description: Breast

The pooled difference in means for the VAS score was -4.1 (CI -4.5 to -3.6, I2 = 90%).Interpretation – Our data showed that HV surgery decreased patients’ perceptions regarding pain. Furthermore, the data confirmed that HV surgery increased patients’ QoL, particularly concerning physical and social domains.